508 research outputs found
Achieving Good Angular Resolution in 3D Arc Diagrams
We study a three-dimensional analogue to the well-known graph visualization
approach known as arc diagrams. We provide several algorithms that achieve good
angular resolution for 3D arc diagrams, even for cases when the arcs must
project to a given 2D straight-line drawing of the input graph. Our methods
make use of various graph coloring algorithms, including an algorithm for a new
coloring problem, which we call localized edge coloring.Comment: 12 pages, 5 figures; to appear at the 21st International Symposium on
Graph Drawing (GD 2013
Drawing Planar Graphs with a Prescribed Inner Face
Given a plane graph (i.e., a planar graph with a fixed planar embedding)
and a simple cycle in whose vertices are mapped to a convex polygon, we
consider the question whether this drawing can be extended to a planar
straight-line drawing of . We characterize when this is possible in terms of
simple necessary conditions, which we prove to be sufficient. This also leads
to a linear-time testing algorithm. If a drawing extension exists, it can be
computed in the same running time
Post-operative bilateral adrenal haemorrhage: A case report
AbstractINTRODUCTIONBilateral adrenal haemorrhage is a rare, but serious, illness carrying an estimated 15% mortality.1,2 The majority of cases occur in patients with acute, stressful illness, however the exact mechanism underlying adrenal haemorrhage remains unclear. This medical emergency carries significant diagnostic difficulty4 with non-specific clinical symptoms and variations in electrolyte abnormalities. Timely treatment is important as it prevents both the acute and long-term sequelae of adrenal failure.PRESENTATION OF CASEThis report describes a medical emergency in a surgical patient following emergency surgery for intra-abdominal sepsis. The patient reported non-specific symptoms of confusion, mild pyrexia and vague abdominal pain during the post-operative phase, with subtle electrolyte abnormalities and a low serum cortisol suggestive of adrenal crisis. Timely medical treatment, with intravenous hydrocortisone and intensive monitoring, and appropriate medical follow-up with addition of long-term fludrocortisone resulted in a satisfactory outcome.DISCUSSIONThis report describes a potentially life-threatening complication of intra-abdominal sepsis with adrenal crisis secondary to bilateral adrenal haemorrhage. In particular, this case highlights the diagnostic difficulty in such surgical patients due to vague symptoms and, in this case, the presence of a presentation variant with acute hyponatraemia and normal potassium.CONCLUSIONThis case highlights the importance of awareness of both the symptoms and signs and variation in electrolyte profile when assessing surgical patients post-operatively. In addition, this case highlights the benefit of early recognition and initiation of treatment and the importance of follow-up as long-term medical management is often required to prevent further relapse
High throughput methodology for synthesis, screening, and optimization of solid state Lithium ion electrolytes
A study of the lithium ion conductor Li3xLa2/3āxTiO3 solid solution and the surrounding composition space was carried out using a high throughput physical vapor deposition system. An optimum total ionic conductivity value of 5.45 Ć 10ā4 S cmā1 was obtained for the composition Li0.17La0.29Ti0.54 (Li3xLa2/3āxTiO3x = 0.11). This optimum value was calculated using an artificial neural network model based on the empirical data. Due to the large scale of the data set produced and the complexity of synthesis, informatics tools were required to analyze the data. Partition analysis was carried out to determine the synthetic parameters of importance and their threshold values. Multivariate curve resolution and principal component analysis were applied to the diffraction data set. This analysis enabled the construction of phase distribution diagrams, illustrating both the phases obtained and the compositional zones in which they occur. The synthetic technique presented has significant advantages over other thin film and bulk methodologies, in terms of both the compositional range covered and the nature of the materials produce
Drawing Graphs within Restricted Area
We study the problem of selecting a maximum-weight subgraph of a given graph
such that the subgraph can be drawn within a prescribed drawing area subject to
given non-uniform vertex sizes. We develop and analyze heuristics both for the
general (undirected) case and for the use case of (directed) calculation graphs
which are used to analyze the typical mistakes that high school students make
when transforming mathematical expressions in the process of calculating, for
example, sums of fractions
Effect of an alkaloidal fraction of Tabernaemontana elegans (Stapf.) on selected micro-organisms
Ethnopharmacological relevance: Bacterial infections remain a significant threat to
human health. Due to the emergence of widespread antibiotic resistance,
development of novel antibiotics is required in order to ensure that effective
treatment remains available. There are several reports on the ethnomedical use of
Tabernaemontana elegans pertaining to antibacterial activity.
Aim of the study: The aim of this study was to isolate and identify the fraction
responsible for the antimicrobial activity in T. elegans (Stapf.) root extracts.
Materials and methods: The active fraction was characterised by thin layer
chromatography (TLC) and gas chromatography ā mass spectrometry (GC-MS).
Antibacterial activity was determined using the broth micro-dilution assay and
antimycobacterial activity using the BACTEC radiometric assay. Cytotoxicity of the
crude extract and fractions was assessed against primary cell cultures; lymphocytes
and fibroblasts; as well as a hepatocarcinoma (HepG2) and macrophage (THP-1)
cell line using the Neutral Red uptake and MTT assays.
Results: The crude root extracts were found to contain a high concentration of
alkaloids (1.2% w/w). GC-MS analysis identified the indole alkaloids, voacangine and
dregamine, as major components. Antibacterial activity was limited to the Grampositive
bacteria and Mycobacterium species, with MIC values in the range of 64 ā
256 Ī¼g/ml. When combined with antibiotics, additive antibacterial effects were
observed. Marked cytotoxicity to all cell lines tested was evident in the MTT and
Neutral Red uptake assays, with IC50 values < 9.81 Ī¼g/ml.Conclusions: This study confirms the antibacterial activity of T. elegans and supports
its potential for being investigated further for the development of a novel antibacterial
compound.National Research Foundationhttp://www.elsevier.com/locate/jethphar
Incidence and risk factors of exposure keratopathy in critically ill patients in an academic hospital complex - a cohort study
https://drive.google.com/file/d/11XauRd8_w4e_c8jgLxEPF4urCvPHclHW/view?usp=sharinghttps://drive.google.com/drive/folders/15cWFPxccGylThfsRch-tJaKg7fI7IFb1?usp=sharinghttps://drive.google.com/drive/folders/1NTHIc69Pd2HCKI1p1Lr2-1qLZ4GewJq7?usp=sharin
Planar and Poly-Arc Lombardi Drawings
In Lombardi drawings of graphs, edges are represented as circular arcs, and
the edges incident on vertices have perfect angular resolution. However, not
every graph has a Lombardi drawing, and not every planar graph has a planar
Lombardi drawing. We introduce k-Lombardi drawings, in which each edge may be
drawn with k circular arcs, noting that every graph has a smooth 2-Lombardi
drawing. We show that every planar graph has a smooth planar 3-Lombardi drawing
and further investigate topics connecting planarity and Lombardi drawings.Comment: Expanded version of paper appearing in the 19th International
Symposium on Graph Drawing (GD 2011). 16 pages, 8 figure
Lombardi Drawings of Graphs
We introduce the notion of Lombardi graph drawings, named after the American
abstract artist Mark Lombardi. In these drawings, edges are represented as
circular arcs rather than as line segments or polylines, and the vertices have
perfect angular resolution: the edges are equally spaced around each vertex. We
describe algorithms for finding Lombardi drawings of regular graphs, graphs of
bounded degeneracy, and certain families of planar graphs.Comment: Expanded version of paper appearing in the 18th International
Symposium on Graph Drawing (GD 2010). 13 pages, 7 figure
Factors associated with the presence and prevalence of contagious ovine digital dermatitis: a 2013 study of 1136 random English sheep flocks
In 2013, a questionnaire was used to gather data on risks for introduction, and factors associated with prevalence, of contagious ovine digital dermatitis (CODD). There were 1136 (28.4%) usable responses from 4000 randomly selected sheep farmers in England. CODD was present in 58% (662) of flocks, with a reported prevalence of CODD lesions of 2.3%. The geometric mean period prevalence of all lameness was 4.2% and 2.8% in CODD positive and negative flocks respectively. Factors associated with a greater risk of presence of CODD were purchasing replacement ewes, not always checking the feet of sheep before purchase, not isolating purchased sheep, foot bathing returning ewes, foot trimming the flock more than twice in the year all compared with not doing these activities and increasing log10 flock size. Farmers who vaccinated sheep with Footvaxā¢ were less likely to report presence of CODD. Factors associated with increasing prevalence of CODD lesions were not always checking the feet of purchased sheep, flocks that mixed with other flocks and sheep that left the farm for summer grazing and later returned. In addition, flocks where farmers followed the current recommended managements for control of footrot, had a lower prevalence of CODD whilst those who used foot bathing and where feet bled during routine foot trimming had a higher prevalence of CODD. The prevalence of CODD decreased with each log10 increase in flock size. We conclude that CODD is an infectious cause of lameness in sheep of increasing importance in GB. Introduction is linked to poor biosecurity with one likely source of the pathogen being introduction of or mixing with infected sheep. As with footrot, prevalence of CODD was lower in flocks where farmers focused on individual treatment to manage lameness and avoided foot bathing and trimming feet. We conclude that most of the currently recommended biosecurity and treatment approaches to control footrot in GB are also effective for control of CODD
- ā¦